Granuloma faciale: a good therapeutic response with the use of topical tacrolimus
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چکیده
منابع مشابه
Granuloma faciale: a good therapeutic response with the use of topical tacrolimus*
Granuloma faciale is a rare dermatosis of chronic course, benign, usually asymptomatic, first described in 1945 by Wingley. It is characterized by the appearance of well-defined, single or multiple papules, plaques and nodules, predominantly located in sun-exposed areas, especially the face. In this work we report the case of a female patient, 58 years old, evolving for ten years with multiple ...
متن کاملGranuloma faciale successfully treated with topical tacrolimus: a case report.
Granuloma eosinophilicum faciale (GF) is a rare chronic inflammatory disorder of unknown etiology. Although the condition is benign, its treatment is often unsatisfactory. We describe a case of a 60-year-old man with GF resistant to therapy with topical corticosteroids and liquid nitrogen. After 4 months of treatment with topical tacrolimus the lesions resolved, with remission lasting for 2 years.
متن کاملSuccessful response to topical tacrolimus for a granuloma faciale in an elderly patient.
plaques, papules or nodules over the dorsa of joints, and GF usually appears as one or a few plaques on the face. In addition, eosinophils and plasma cells are prominent in GF, whereas neutrophils are plentiful in erythema elevatum diutinum [1] . GF is often quite resistant to therapy [2–6] . Topical calcineurin inhibitors may represent a useful alternative to topical corticosteroids for the tr...
متن کاملGranuloma faciale effectively treated with topical pimecrolimus.
Granuloma faciale (GF) is a rare skin disorder with a chronic-relapsing course. Cutaneous lesions affect predominantly the face of middle-aged Caucasian men with characteristic reddish papules, nodules, or plaques; however, various atypical cases with unusual morphology or extra facial involvement have been reported (1-3). Despite many treatment options, both surgical and medical, GF remains th...
متن کاملSuccessful Treatment of Granuloma Faciale with Topical Tacrolimus: A Case Report and Immunohistochemical Study
We report the case of a 55-year-old Japanese patient with granuloma faciale (GF) successfully treated with topical tacrolimus and describe the immunohistochemical study. Immunohistochemical staining revealed that the patient's granuloma contained CD3(+), CD4(+), CD8(+), CD68(+) and CD163(+) cells. Interestingly, these cells contained granulysin(+) T cells and lacked Foxp3(high+) regulatory T ce...
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ژورنال
عنوان ژورنال: Anais Brasileiros de Dermatologia
سال: 2015
ISSN: 0365-0596
DOI: 10.1590/abd1806-4841.20153339